Prescription Zyban (value) Drug Information

BEFORE USING THIS MEDICINE: WARNING: ANTIDEPRESSANT MEDICINES MAY INCREASE THE RISK OF SUICIDAL THOUGHTS AND BEHAVIORS IN CHILDREN AND ADOLESCENTS, AND POSSIBLY ADULTS, WHO HAVE SEVERE DEPRESSION OR CERTAIN OTHER MENTAL OR MOOD DISORDERS. Children, adolescents, and adults who take this medicine should be monitored daily for any worsening of their condition, thoughts of hurting themselves, or any other sudden or unusual changes in mood or behavior, especially during the first few months after starting this medicine and after any change in the dose of this medicine. If any of these serious side effects occur, contact the doctor immediately. DO NOT TAKE THIS MEDICINE if you are already taking bupropion to stop smoking, taking a monoamine oxidase inhibitor (MAOI), or thioridazine. ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you are taking other antidepressants or psychiatric medicines, certain high blood pressure medicines (e.g.,"beta-blockers"), certain heart medicines (e.g., propafenone, flecainide), decongestants, diabetes medicine, diet pills, levodopa, HIV protease inhibitors (e.g., ritonavir), quinolone antibiotics (e.g., ciprofloxacin, ofloxacin), seizure medicine, theophylline, tranquilizers, tramadol, warfarin, narcotic pain relievers (e.g., acetaminophen with codeine), or products containing nicotine (e.g., patches or gum). Also report the use of drugs which might increase seizure risk (decrease seizure threshold) when combined with bupropion such as phenothiazines (e.g., thioridazine), tricyclic antidepressants (e.g., amitriptyline), isoniazid (INH), or theophylline among others. Consult your pharmacist for details. DO NOT START OR STOP any medicine without doctor or pharmacist approval. Inform your doctor of any other medical conditions including any mental or mood disorders (such as bipolar disorder), kidney disease, liver disease, diabetes, head injury, tumors (e.g., brain or spinal cord), or history of drug or alcohol addiction, allergies, pregnancy, or breast-feeding. DO NOT USE THIS MEDICINE if you have a history or eating disorders (e.g., anorexia, bulimia). If you experience anxiety, agitation, panic attacks, difficulty sleeping, irritability, hostility, impulsive feelings, severe restlessness, or worsening of depression contact your doctor as soon as possible. These may be signs that your condition is worsening or that your treatment with this medicine should be evaluated. POSSIBLE SIDE EFFECTS: SIDE EFFECTS, that may go away during treatment, include restlessness, dizziness, dry mouth, difficulty sleeping, headache, nausea, vomiting, constipation, change in weight, or tremor. If they continue or are bothersome, check with your doctor. CHECK WITH YOUR DOCTOR AS SOON AS POSSIBLE if you experience palpitations. CONTACT YOUR DOCTOR IMMEDIATELY if you experience seizures, severe nervousness or anxiety, agitation, panic attacks, difficulty sleeping, feelings of irritability or hostility, impulsive behavior or other unusual changes in behavior, severe restlessness, worsening feelings of depression, thoughts of hurting yourself, or any other mental or mood changes.